BRCA1- and BRCA2-associated hereditary breast and ovarian cancer (HBOC) is characterized by an increased risk for male and female BC, ovarian cancer (including fallopian tube and primary peritoneal cancers), and, to a lesser extent, other cancers, such as prostate, pancreatic, and melanoma [10]. Here, BRCA1 is linked to Hereditary breast and ovarian cancer syndrome.