When comparing patients with and without diabetes, we found that KMO activity was increased more in diabetic patients (median = 0.765, IQR = 0.498–1.095) than in non-diabetic patients (median = 0.545, IQR = 0.364–0.802); this was supported by a Mann–Whitney U test (U = 820, p = 0.039, r = 0.257). The gene discussed is KMO; the disease is diabetes mellitus.