Inflammation plays an important role in the progression of atherosclerosis by impairing cardiovascular endothelial function, mobilizing leukocytes, and inducing the expression of proinflammatory cytokines such as elastase, myeloperoxidase, and free oxygen radicals that contribute to oxidative stress, ischemic myocardial damage, and ischemia-reperfusion injury [37,38,39]. This evidence concerns the gene MPO and atherosclerosis.