Immunohistochemical analysis of the grade 3 metastatic NET showed wild-type p53 expression, retained retinoblastoma (Rb) protein, no α-thalassemia/mental retardation syndrome X-linked (ATRX) loss, and strong expression of somatostatin receptor 2 (SSTR2) in 70% of the tumor cells. This evidence concerns the gene SSTR2 and thalassemia.