Hsieh et al. [28] reported that in patients with HCC, FibroQ has better predictive values for significant fibrosis (METAVIR ≥ 3) and cirrhosis (METAVIR = 4) than APRI, but it is equal to the AST/ALT ratio with AUC values of 0.783 and 0.791, respectively. This evidence concerns the gene GPT and Cirrhosis.