CALCA and cancer: Xu et al. (2019) [27] evaluated biomarkers in 3118 febrile episodes among pediatric cancer patients, showing PCT’s limited discriminatory capacity for GNB (AUC = 0.68), significantly inferior to IL-10 (AUC = 0.81, p < 0.001) and IL-6 (AUC = 0.77, p < 0.001).