Srinivasan et al. (2021) [13] found no significant difference in IL-8 levels between pediatric FN episodes with microbiologically confirmed infections (median: 613.6 pg/mL) and non-infectious fever (263.7 pg/mL; p = 0.41), with an AUC of 0.551—barely exceeding random chance. This evidence concerns the gene CXCL8 and infection.