Urbonas et al. (2012) [17] demonstrated that IL-10 < 18 pg/mL had a negative predictive value of 83% for excluding bacteremia/sepsis in pediatric FN, with 92% specificity (PPV = 86%, AUC = 0.87) and a sensitivity CI ranging from 39% to 94%. This evidence concerns the gene IL10 and bacterial infectious disease with sepsis.