ANLN is also closely associated with m6A modification; Hao et al. [38] found that the upregulation of METTL3 enhances m6A modification on ANLN mRNA, while YTHDF1 directly binds to the m6A sites within ANLN mRNA to maintain its stability, thereby promoting bone metastasis in HCC. This evidence concerns the gene METTL3 and hepatocellular carcinoma.