KRAS and familial pancreatic carcinoma: Mutations in the KRAS gene are largely involved in the development of pancreatic cancer and activate signal pathways, such as Ras/Raf/MEK/ERK, PI3K/AKT, and RalGDS, to promote cell proliferation, enhance sugar metabolic pathways, and promote cancer formation and progression by controlling reactive oxygen species (ROS) [4,5].