Using this strict approach, we selected two genes associated with a detrimental prognosis: B3GNT7 and CTSV in BRCA2-mut breast cancers, and three with a favorable prognosis: CD6, CXCL9, and CXCL13 in BRCA1-mut ovarian cancers (Figure 4A). This evidence concerns the gene CTSV and breast cancer.