Research indicates that EVs containing LINC00622 derived from adipose mesenchymal stem cells increase the expression of γ-aminobutyric acid type b receptor 1 (GABBR1) in NB cells by mediating the transcription factor androgen receptor to upregulate the activity of GABBR1, thereby inhibiting the proliferation, invasion, and migration of NB cells [78] (Figure 3A). This evidence concerns the gene AR and neuroblastoma.