SOST and Miyoshi myopathy: MM patients who presented with fractures at diagnosis were found to have very high levels of circulating sclerostin compared with all others (p < 0.01), while sclerostin serum levels correlated negatively with bALP (r = −0.541; p < 0.0001) and positively with CTX (r = 0.524; p < 0.0001) [105].