Baseline CFH concentrations were significantly higher in patients with advanced cSCC (median = 347.7 pg/mL) compared to high-risk cSCC (median = 302.7 pg/mL; p = 0.0305, Mann–Whitney U test; difference between medians: 44.97 pg/mL; Hodges–Lehmann estimator: –72.28 pg/mL) (Figure 1A). The gene discussed is CFH; the disease is skin squamous cell carcinoma.