To assess the clinical significance of the expression of BTLA, CD160, SPN, TIM3, VISTA, and TIGIT in Ps, we analyzed associations of those expressions with prognostic factors, including gender, type of Ps, psoriatic arthritis activity, clinical course, age and duration, and also PASI, WBC, neutrophils, lymphocytes, CRP and OB level. The gene discussed is TIGIT; the disease is psoriatic arthritis.