To assess the clinical significance of the expression of BTLA, CD160, SPN, TIM3, VISTA, and TIGIT in Ps, we analyzed associations of those expressions with prognostic factors, including gender, type of Ps, psoriatic arthritis activity, clinical course, age and duration, and also PASI, WBC, neutrophils, lymphocytes, CRP and OB level. This evidence concerns the gene CRP and psoriatic arthritis.