Consistently, among them, four are known C1B genes: CHST4 (encoding CarboHydrate sulfotransferase 4), CSDC2 (encoding Cold Shock Domain Containing C2), NME5 (encoding Non-Metastasis cell 5 protein) and PINK1 (encoding PTEN-Induced Kinase 1, whose high expression are well-established good prognosis biomarkers in ACC [21,29]. This evidence concerns the gene PINK1 and adrenal cortex carcinoma.