Figure 4A shows representative immunohistochemistry (IHC) staining images demonstrating the fraction of cells expressing SEMA7A in ACC tissues compared to normal adrenal gland tissue and adrenocortical adenoma (benign tumor). Quantification (Figure 4B) is consistent with the bimodal distribution of SEMA7A expression observed at the transcript level. This evidence concerns the gene SEMA7A and adrenal cortex adenoma.