SOD1 and liver disorder: Hepatic diseases are also associated with the accumulation of cellular injuries caused by the dysregulation of REDOX homeostasis, which can result from an increased production of reactive oxygen species (ROS) and decreased antioxidant defense enzymes such as superoxide dismutase (SOD), glutathione peroxidase (GPX), and catalase (CAT) enzymes, resulting in cellular oxidative stress [21].