Electrolyte disturbances, most frequently hypokalemia, were corrected promptly with intravenous potassium replacement; mild to moderate hyponatremia received intravenous isotonic saline (0.9% sodium chloride solution) as part of fluid and electrolyte management, based on individual clinical and laboratory findings; and patients who exhibited clinically relevant hypoalbuminemia received targeted protein supplementation with human serum albumin solutions. This evidence concerns the gene ALB and Hyponatremia.