KRT3 and cancer: Compared to the CK3 group, the significant differential metabolic pathways in the T3 group were glyoxylate and dicarboxylate metabolism, a glucagon signaling pathway, citrate cycle (TCA cycle), carbon metabolism, central carbon metabolism in cancer, purine metabolism, amino acid metabolism, fructose and manmose metabolism, inositol phosphate metabolism, etc. (Figure 5K).