Subsequently, these mice were exposed to DSS, and it was observed that SLAMF7 silencing ameliorated DSS-induced colitis, as evidenced by reduced weight loss (Figure 7(c)), increased colon length (Figure 7(d)), a lower DAI score (Figure 7(e)), and an increased number of goblet cells (Figure 7(f)) compared to those of WT-siNC mice. This evidence concerns the gene SLAMF7 and colitis.