Previous studies have reported Akkermansia muciniphila and Christensenellaceae R_7 as signatures of a healthy gut,28,29 and Enterococcus, Streptococcus, Erysipelatoclostridium, and Veillonella have been linked to gut disorders.30 We observed that patients with IBD exhibit a microbiome profile distinct from that of DSS-treated slamf7-/- mice (Figure S6a). The gene discussed is SLAMF7; the disease is inflammatory bowel disease.