ESR1 and obesity due to melanocortin 4 receptor deficiency: In ER+/HER2- we found no association (ORadj=0.97 [95%CI = 0.49–1.96]), and there was a less prominent association in DNBC tumors (ORadj=0.88 [95%CI = 0.49–1.57]), among patients with obesity compared to those with normal weight.