CXCL8 and infection: Supporting this, previous studies examining the impact of different infection models on the response of rainbow trout (Oncorhynchus mykiss) to Yersinia ruckeri have revealed significant differences in inflammatory (IL-1b1 and IL-8) and anti-microbial (Cath-1 and Cath-2) responses between IP injected fish and infected cohabitants [71].