At the protein level, the observed reductions of GLUT1 and GLUT 3 levels in AD animal models compared to controls, both in STZ-icv treated rats (Deng et al. 2009; Salkovic-Petrisic et al. 2014) and NSE/hPS2m Tg mice (Lee et al. 2013), mirror the mRNA-level differences. This evidence concerns the gene ENO2 and Alzheimer disease.