GRN and infection: A difference in progranulin levels was revealed in the intra-amniotic infection, sterile intra-amniotic inflammation and negative amniotic fluid (infection: median 75.3 pg/mL, IQR 52.3-150.3; sterile: median 54.0 pg/mL, IQR: 46.9–72.7; negative: median 39.1 pg/mL, IQR: 34.0-49.2; p < 0.0001; Fig. 1B) subgroups, both in the crude analysis (p < 0.0001) and after adjustment for gestational age (p = 0.001).