From the Autoimmune Diseases Explorer database (https://adex.genyo.es/)65,66, we observed a decreased expression of NRBP2 mRNA level within the synovial membrane samples obtained from RA patients, whereas NRBP1 mRNA level was similar in healthy group and RA patients (Fig. 6f). The gene discussed is NRBP1; the disease is rheumatoid arthritis.