These rich EHR data have allowed investigation of questions related to the COVID-19 pandemic and HIV, including identification of an elevated risk of poor COVID-19 outcomes in people living with HIV with a low cluster of differentiation 4 (CD4) count (<200 cells/μL) and racial disparities with COVID-19 positivity among people living with HIV, in addition to both individual and area-level social determinants of health with COVID-19 outcomes [2,13-15]. The gene discussed is CD4; the disease is COVID-19.