Based on the degree value of the topological network, IFNG, EGFR, MYC, CXCR4, MAPK8, CASP1, TNFSF10, CTSB, FAS, FOXO1, FOXO3 were obtained, these 11 genes are the core genes related to RA autophagy, and these degree values are ranked in Table 2. This evidence concerns the gene IFNG and rheumatoid arthritis.