And 11 RA autophagy-related core genes (IFNG, EGFR, MYC, CXCR4, MAPK8, CASP1, TNFSF10, CTSB, FAS, FOXO1, FOXO3) were obtained by screening the PPI network, and there were differences in expression in the training set (P < 0.001). Here, MYC is linked to rheumatoid arthritis.