And 11 RA autophagy-related core genes (IFNG, EGFR, MYC, CXCR4, MAPK8, CASP1, TNFSF10, CTSB, FAS, FOXO1, FOXO3) were obtained by screening the PPI network, and there were differences in expression in the training set (P < 0.001). Here, TNFSF10 is linked to rheumatoid arthritis.