NF1 and neoplasm: Linear regression analysis to quantify the impact of tumor volume at diagnosis on a potentially impaired VA showed no significant correlation of tumor volume and logMAR values of the worse eye (WSE) at diagnosis when including all patients (R2 = 0.038, p = 0.29, see Fig. 3A) or patients with NF-1 (R2 = 0.037, p = 0.85, see Fig. 3A).