First, both ALDH1A1/2 activity and ROS levels correlated with the ELN22 prognostic groups (groups of prognostic classification based on molecular genetic features defined by European LeukemiaNet in year 2022), with higher ALDH1A1/2 and ROS levels in the unfavorable/intermediate groups, when compared to favorable AML. Here, ALDH1A1 is linked to acute myeloid leukemia.