RT-qPCR analysis further confirmed that the mRNA expression levels of M1 markers (CD11c, CD86, and iNOS) were significantly elevated in the T2DM-SED group (Figure 4F–H), whereas M2 markers (CD206, CD163, and Arg1) were significantly downregulated (Figure 4J–L). This evidence concerns the gene CD86 and type 2 diabetes mellitus.