For example, swimming has been reported to attenuate pulmonary inflammation and apoptosis in T1DM mice [27]; voluntary exercise alleviated pulmonary inflammation in T2DM rats by modulating NF-κB and Nrf2 signaling pathways [26]; and HIIT was shown to mitigate diabetic lung injury by regulating inflammation, oxidative stress, and apoptosis [25]. This evidence concerns the gene NFKB1 and type 2 diabetes mellitus.