A recent study indicated that induced pluripotent stem cells (iPSC)-derived astrocytes from patients with autism also exhibited overexpression of immune relevant genes, such as TGFB1, TGFB2, and IL6 that was associated with DNA hypomethylation of TGFB2, IL6, and TNFA gene promoter regions [33]. The gene discussed is TGFB2; the disease is autism.