PIM1 and coronary atherosclerosis: PDGF-BB promotes VSMC phenotypic switching by downregulating MiRNA-214 and upregulating Pim-1, while MiRNA-214 inhibits this process by suppressing Pim-1 expression and EMT-mediated migration, with Pim-1 overexpression counteracting MiRNA-214’s effects via STAT3, AKT, and ERK signaling, contributing to coronary atherosclerosis progression [115].