These properties of ghrelin have led to studies investigating its use as a therapy for several heart conditions, and one study showed that ghrelin administration significantly improved heart function and decreased LV remodeling and fibrosis in a mouse model of dilated cardiomyopathy in which cardiomyopathy occurs through a knock-in of the deletion mutation deltaK210 in cardiac troponin [23]. The gene discussed is GHRL; the disease is dilated cardiomyopathy.