NLRP3 and age-related macular degeneration: Activated NLRP3 inflammasomes and inflammation have been detected in blinding diseases and the role of NLRP3 in the etiology and development of age-related eye diseases such as age-related macular degeneration (AMD), diabetic retinopathy, glaucoma and other chronic ocular diseases has been established [67,299,300,301].