BIRC5 and Miyoshi myopathy: Furthermore, in a similar manner to that which they observed during the evaluation of BM-MSC–CAR T cell cross-talk [26], Holthof and colleagues demonstrated that use of the FL118 inhibitor, which suppressed activity of Survivin and Mcl-1, successfully overcame BM-MSC-mediated resistance of MM cells to CAR NK cell-induced apoptosis [36].