APOE and Alzheimer disease: Bootstrapped mediation analysis exhibited that voxel‐wise concordance in the right CAU partially mediated the negative association between plasma Aβ42 and language function in APOE ε4 carriers with AD (indirect effect = −0.0456, 95% CI [−0.1359, −0.0009], Figure 4), after adjustment for age, sex, and years of education.