Previous studies have shown that defects in LAMA5 lead to a variety of developmental abnormalities, including osteogenesis imperfecta, pulmonary hypoplasia, and nephrotic syndrome.[27] Recent research has found that in cardiac‐like organs, LAMA5 is an important factor in promoting the maturation of cardiomyocytes, with a 20% decrease in myocardial contractile force following LAMA5 knockdown. This evidence concerns the gene LAMA5 and Pulmonary hypoplasia.