The stratified analysis of tumor types in our meta-analysis showed that under 5 genetic models (OR = 1.733, 95% CI: 1.242–2.417, p=0.106, I2 < 50%; OR = 1.294, 95% CI: 1.112–1.505, p=0.281, I2 < 25%; OR = 1.469, 95% CI: 1.073–2.012, p=0.045, I2 < 75%; OR = 1.250, 95% CI: 1.067–1.465, p=0.028, I2 < 75%; OR = 1.208, 95% CI: 1.054–1.386, p=0.830, I2 < 25%), HOTAIR rs920778 gene mutation significantly increased the risk of CC in Asians, which confirms that the rs920778 polymorphism increases the risk of CC in Asian ethnic groups and suggests that it may serve as a prognostic marker for CC. Here, HOTAIR is linked to neoplasm.