Given its vital role in promoting the survival of dopaminergic neurons, GDNF has also demonstrated its ability to prevent neurotoxin-induced death of dopamine neurons and to facilitate functional recovery in various animal models of Parkinson’s disease (Kearns and Gash, 1995; Tomac et al., 1995; Airaksinen and Saarma, 2002; Barker et al., 2020). Here, GDNF is linked to Parkinson disease.