Fang Lichun (86) also used RNA Seq technology to reveal the diversity of physiological status of bovine tuberculosis under different infection conditions, and screened and verified that IL-8, LTA, CRP, BCL2 and CHI3L1 are molecular markers of bovine tuberculosis with diagnostic value, providing a new target for early diagnosis, disease monitoring and treatment of tuberculosis. The gene discussed is CXCL8; the disease is Tuberculosis, Bovine.