Subsequent multivariate analysis identified the following independent risk factors influencing OS: AFP ≥ 400 ng/mL (p = 0.001); moderate malnutrition (p < 0.001); severe malnutrition (p = 0.006); serum albumin <35 g/L (p < 0.001); maximum tumor diameter >5 cm (p = 0.013); and tumor number ≥3 (p = 0.043). This evidence concerns the gene AFP and nutritional deficiency disease.