CD6 and autoimmune uveitis: These results align with previous reports of exacerbated CIA and cGvHD-induced lupus-like disease, as well as antiviral humoral responses in CD6-deficient mice (22, 25, 26) but contradict those reporting attenuated EAE, autoimmune uveitis and imiquimod-induced psoriasis disease models (3, 21, 24).