In this study, we investigated whether IFN-γ-transfected BMSCs combined with QSFZYL affects the progression of lung adenocarcinoma through the JAK2/STAT3 pathway through Western blotting and qPCR analyses of the expression of JAK2/STAT3 pathway-related proteins and genes in intervention groups. The gene discussed is STAT3; the disease is lung adenocarcinoma.