Moreover, the 20 top KEGG pathway enrichments were shown in the bubble chart (Figure 2C), which also suggested the possible mechanisms of QSFZYL resisting lung adenocarcinoma through multiple signaling pathways, lipid and atherosclerosis, chemical carcinogenesis-receptor activation, PI3K-Akt signaling pathway and etc (Figure 2E). This evidence concerns the gene AKT1 and atherosclerosis.