RUNX1 intronic transcript 1 binds to the N6-methyladenosine m6A reader IGF2BP1, promotes the formation of the IGF2BP1 biomolecular condensate, and improves the stability of GPX4 mRNA, which increases the expression of GPX4, blocks ferroptosis, and promotes breast cancer development (16). The gene discussed is GPX4; the disease is breast carcinoma.