described a differential requirement of CSF-1R signaling in PDGFB-induced NPC-like versus in HRAS-driven gliomas (59) and the IL-1β pathway was shown to promote PDGFB-driven GB, through induction of monocyte chemoattractant protein (MCP)1-mediated recruitment of MDMs (60). The gene discussed is PDGFB; the disease is central nervous system cancer.