ALDH2 and myocardial infarction: Therefore, we constructed a ferroptosis model in vitro using erastin-induced human umbilical venous ECs (HUVECs) and a post-MI ventricular remodeling mouse model through ligating the left anterior descending (LAD) artery, so as to investigate the potential mechanism by which ALDH2 signaling influenced the functions of Tan I in vascular EC ferroptosis, angiogenesis, as well as ventricular remodeling post-MI.