LGALS9 and cancer: Interestingly, Gal-9 also eradicated cancer cells resistant to conventional therapies, like cytarabine-resistant acute myeloid leukemia (AML) (Choukrani et al., 2023), imatinib-resistant chronic myelogenous leukemia (Kuroda et al., 2010), and apoptosis-resistant colon cancer (Wiersma et al., 2015).