Additional studies have focused on the genetic enhancement of disease resistance across various animal species, including cows engineered to express a human lysozyme gene to combat mastitis and cows with edited versions of the SP110 (Speckled 110kDa, also known as intracellular pathogen resistance 1, Ipr1) gene to confer resistance to tuberculosis (Wu et al. 2015). The gene discussed is SP110; the disease is mastitis.