Finally, antiphospholipid syndrome (APS) may be on the list of differential diagnosis in our clinical case, as anticardiolipin IgG and IgM was found to be increased in the serum on the first occasion (36.7.2; normal range ≥40IU/ml) [27], which normalized after 6 month till 23.2 IU/ml; albeit IgG/IgM antiphospholipid antibodies (respectively, IgG 2.8 and IgM 5.8; normal range <10MPLU/ml) and lupus anticoagulant (1.1) were found to be negative. Here, CD40LG is linked to antiphospholipid syndrome.