DepMap analysis revealed the overall dependency of cancer cell lines on ABC transporter genes such as ABCG2, ABCG1, ABCC4, ABCA2, ABCA3, ABCC2, ABCC3, ABCC6, ABCC7 (CFTR), and ABCC9, with ABCC6 and ABCC7 showing notably high dependence. Here, ABCC9 is linked to cancer.