CAD and rheumatoid arthritis: Activated CPs included ‘mitochondrial dysfunction,’ ‘role of osteoclasts in rheumatoid arthritis signalling,’ ‘neutrophil degranulation,’ ‘phagosome formation,’ ‘integrin cell surface interactions’ and ‘extracellular matrix organization.’ IPA also identified upstream regulators that were predicted to be activated or inhibited based on gene expression changes of transcriptional target molecules in each transcriptome (Table S3).