Analysis of another distinct series modeling breast cancer progression (Fig. 5A)—EGFR-transformed murine mammary gland cells (NME) compared to their isogenic counterparts harvested from lung metastases (LM2) [33] demonstrated similar findings, where FAO-dependent migration from lipolytic products were required to sustain LM2 cell migration (Fig. 5B and C). Here, EGFR is linked to breast carcinoma.